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Nephrosis is any of various forms of kidney disease (nephropathy). In an old and broad sense of the term, it is any nephropathy,[1] but in current usage the term is usually restricted to a narrower sense of nephropathy without inflammation or neoplasia,[2] in which sense it is distinguished from nephritis, which involves inflammation. It is also defined as any purely degenerative disease of the renal tubules.[1] Nephrosis is characterized by a set of signs called the nephrotic syndrome.[2] Nephrosis can be a primary disorder or can be secondary to another disorder.[2] Nephrotic complications of another disorder can coexist with nephritic complications. In other words, nephrosis and nephritis can be pathophysiologically contradistinguished, but that does not mean that they cannot occur simultaneously.[citation needed]

Types of nephrosis include amyloid nephrosis and osmotic nephrosis.[citation needed]


Disability-adjusted life year for nephritis and nephrosis per 100,000 inhabitants in 2004.[3]
  no data
  less than 40
  more than 840


  1. ^ a b Elsevier, Dorland's Illustrated Medical Dictionary, Elsevier.
  2. ^ a b c Nephrosis at the US National Library of Medicine Medical Subject Headings (MeSH)
  3. ^ "WHO Disease and injury country estimates". World Health Organization. 2009. Retrieved Nov 11, 2009.

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